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Pre-eclampsia Integrated Estimate of RiSk (PIERS)

The Pre-eclampsia Integrated Estimate of RiSk (PIERS) study is a multicentre international study funded by the Canadian Institutes of Health Research (CIHR) , the World Health Organization UNDP/UNFPA/WHO/World Bank Special Programme of Research, Development and Research Training in Human Reproduction, Preeclampsia Foundation, International Federation of Obstetricians and Gynecologists (FIGO), Michael Smith Foundation for Health Research (MSFHR), and Child and Family Research Institute (CFRI)

The purpose of this research is to develop the first pre-eclampsia classification system based on that system’s ability to predict adverse maternal (& perinatal) outcomes. 

Development of the fullPIERS models has been completed and the project is currently into its next phase: external validation. Validation will take place in high and low risk clinical settings in Developed and Developing World centres, for both pre-eclampsia and the other hypertensive disorders of pregnancy. 

The miniPIERS model is being developed and validated in low and middle income countries with funding from the Bill & Melinda Gates Foundation, CIHR, WHO, USAID, Rockefeller Foundation, FIGO and Preeclampsia Foundation. 

The PIERS Study Group welcomes any international centres interested in joining the project for future implementation studies.